Article

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

2017-05-31

Abstract excerpt

Identification of coding variant associations for complex diseases offers a direct route to biological insight, but is dependent on appropriate inference concerning the causal impact of those variants on disease risk. We aggregated coding variant data for 81,412 type 2 diabetes (T2D) cases and 370,832 controls of diverse ancestry, identifying 40 distinct coding variant association signals (at 38 loci) reaching sig...

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Literature Corpus work: abb54e28-a908-554e-a000-2162e11f2b99
DOI: 10.1101/144410

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