Article

Localized mRNAs and protein synthesis in cortical layer 1

2025-11-24

Abstract excerpt

<h4>Summary</h4> Cortical layer 1 plays an essential role for brain function, integrating many streams of information and undergoing synaptic plasticity during learning. Yet, we understand little of the underlying molecular processes, and whether they are specialized to achieve layer-specific functions. Here, we show that layer 1 and its synapses are metabolically active. Using laser capture RNA-sequencing and fl...

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Literature Corpus work: ab8e8ef5-75c8-55b4-9f0a-8db1d29f227a
DOI: 10.1101/2025.11.23.689989

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