Article

Laminar organization of pyramidal neuron cell types defines distinct CA1 hippocampal subregions

2025-06-05

Abstract excerpt

<title>Abstract</title> <p>Investigating the cell type organization of hippocampal CA1 is essential for understanding its role in memory and cognition and its susceptibility to neurological disorders like Alzheimer’s disease and epilepsy. Multiple studies have identified different organizational principles for gene expression and how it reflects cell types within the CA1 pyramidal layer including gradients or mos...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 40128350-875f-5792-9ae7-6f454e0571f2
DOI: 10.21203/rs.3.rs-6581037/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Laminar organization of pyramidal neuron cell types defines distinct CA1 hippocampal subregionsDOI 10.21203/rs.3.rs-6581037/v1Read

Molecular Expression Profiles of Morphologically Defined Hippocampal Neuron Types: Empirical Evidence and Relational InferencesSemantic proximity Read

Morpho-electric and transcriptomic divergence of the layer 1 interneuron repertoire in human versus mouse neocortexSemantic proximity Read

Homologous laminar organization of the mouse and human subiculumSemantic proximity Read

Molecular Diversity Among Adult Human Hippocampal and Entorhinal CellsSemantic proximity Read

Gene expression levels assessed by CA1 pyramidal neuron and regional hippocampal dissections in Alzheimer's diseaseSemantic proximity Read

Differential vulnerability of CA1 pyramidal neuron cell types in the 5xFAD Alzheimer’s disease mouse modelSemantic proximity Read

HippoGenes: A robust workflow for subregional transcriptomic profiling of the human hippocampusSemantic proximity Read

Localized mRNAs and protein synthesis in cortical layer 1Semantic proximity Read

Transcriptional networks predating cognition-associated pyramidal lineages are restructured by erythropoietinSemantic proximity Read

Ontogenesis of the pyramidal cell of the mammalian neocortex and developmental cytoarchitectonics: a unifying theory.Semantic proximity Read

Transcriptomic diversity of amygdalar subdivisions across humans and nonhuman primatesSemantic proximity Read

Hippocampal development - old and new findings.Semantic proximity Read