Article

The <i>Chlamydia</i> type III effector TarP alters the dynamics and organization of host cell focal adhesions

2018-01-20

Abstract excerpt

The human pathogen Chlamydia trachomatis targets epithelial cells lining the genital mucosa. We observed that infection of various cell types, including fibroblasts and epithelial cells resulted in the formation of unusually stable focal adhesions that resisted disassembly induced by the myosin II inhibitor, blebbistatin. Super-resolution microscopy revealed in infected cells the vertical displacement of paxillin...

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Literature Corpus work: ab86f44c-693f-5f0c-b065-2c6ab08ca6dd
DOI: 10.1101/250563

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