Article
Targeted Disruption of Chlamydia trachomatis Invasion by in Trans Expression of Dominant Negative Tarp Effectors.
Frontiers in cellular and infection microbiology - 1 Jan 2016
Parrett Christopher J, Lenoci Robert V, Nguyen Brenda, Russell Lauren, Jewett Travis J
Abstract excerpt
Chlamydia trachomatis invasion of eukaryotic host cells is facilitated, in part, by the type III secreted effector protein, Tarp. The role of Tarp in chlamydiae entry of host cells is supported by molecular approaches that examined recombinant Tarp or Tarp effectors expressed within heterologous systems. A major limitation in the ability to study the contribution of Tarp to chlamydial invasion of host cells was...
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