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The <i>Chlamydia</i> protein CpoS modulates the inclusion microenvironment and restricts the interferon response by acting on Rab35

2022-02-18

Abstract excerpt

<h4>ABSTRACT</h4> The obligate intracellular bacterium Chlamydia trachomatis inserts into the membrane of its vacuole (the inclusion) a family of poorly characterized Inc proteins. While the Inc CpoS was recently revealed as a critical suppressor of host cellular immune surveillance, the underlying mechanism remained unknown. By complementing a cpoS mutant with modified variants of CpoS, we found that CpoS bloc...

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Literature Corpus work
864fcd11-e9dc-587d-84d2-4040fc77efff
DOI
10.1101/2022.02.18.481055
Open publication

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The <i>Chlamydia</i> protein CpoS modulates the inclusion microenvironment and restricts the interferon response by acting on Rab35DOI 10.1101/2022.02.18.481055
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