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Article

Association between sphingomyelin levels and gut microbiota abundance: a two-sample Mendelian randomization study

2024-02-02

Abstract excerpt

<h4>Background: </h4> Several previous observational studies have shown that abnormal sphingomyelin metabolism may be implicated in the pathogenesis of Alzheimer's disease. To determine the causal relationship between sphingolipid abundance and gut microbiota abundance at the genetic level, we conducted a Mendelian randomization (MR) investigation. Methods We first used the TwoSampleMR and MRPRESSO packages for c...

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Literature Corpus work
ab6ea3e8-d5c0-53ab-ac0b-b97d13043650
DOI
10.21203/rs.3.rs-3869702/v1
Open publication

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