Article
A novel long non-coding RNA, Nostrill, regulates iNOS gene transcription and neurotoxicity in microglia.
2020-10-19
Abstract excerpt
<title>Abstract</title> <p><bold>Background</bold> Microglia are resident immunocompetent and phagocytic cells in the CNS. Pro-inflammatory microglia, stimulated by environmental microbial signals such as bacterial lipopolysaccharide (LPS), viral RNAs, or inflammatory cytokines, are neurotoxic and associated with pathogenesis of several neurodegenerative diseases. Long non-coding RNA (lncRNA) are emerging as impo...
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Identifiers and source
- Literature Corpus work
- ab6e9dfe-271a-5e7f-a3a4-cef75d8ac686
- DOI
- 10.21203/rs.3.rs-93478/v1
