Article

Oral Ursodeoxycholic Acid Therapy Failed to Mitigate SARS-CoV-2 Omicron Infection

2024-09-08

Abstract excerpt

<title>Abstract</title> <p>Background Ursodeoxycholic acid (UDCA) was reported to reduce susceptibility to SARS-CoV-2 infection by downregulating farnesoid X receptor (FXR) -ACE2 signaling. However, we found a different story in real-world clinical studies. Methods We attempted to verify whether UDCA can effectively prevent SARS-CoV-2 transmission or have positive therapeutic effects in a real-world clinical st...

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Literature Corpus work: ab24d3de-2204-5181-b6a6-899a1a4625ef
DOI: 10.21203/rs.3.rs-4837114/v1

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