Article

Oral Ursodeoxycholic Acid Therapy Failed to Mitigate SARS-CoV-2 Omicron Variants BA.5.2 Infection

2023-06-13

Abstract excerpt

Ursodeoxycholic acid (UDCA) was reported to reduce susceptibility to SARS-CoV-2 infection by downregulating farnesoid X receptor (FXR) -ACE2 signaling. However, we found a different story in real-world clinical studies. We attempted to verify whether UDCA can effectively prevent SARS-CoV-2 transmission or have positive therapeutic effects in a real-world clinical study. We performed a retrospective study, collecte...

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Literature Corpus work: 5bcd551e-22b9-543e-a0f1-5894b47f0e0d
DOI: 10.2139/ssrn.4465488

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