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Article

Oral Ursodeoxycholic Acid Therapy Failed to Mitigate SARS-CoV-2 Omicron Variants BA.5.2 Infection

2023-03-27

Abstract excerpt

<h4>Background: </h4> Ursodeoxycholic acid (UDCA) was reported to reduce susceptibility to SARS-CoV-2 infection by downregulating farnesoid X receptor (FXR) -ACE2 signaling. However, we found a different story in real-world clinical studies. Objectives We attempted to verify whether UDCA can effectively prevent SARS-CoV-2 transmission or have positive therapeutic effects in a real-world clinical study. Methods W...

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Identifiers and source

Literature Corpus work
f72c7747-e4d3-5e9b-be81-49d0bea232fb
DOI
10.21203/rs.3.rs-2717720/v1
Open publication

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Oral Ursodeoxycholic Acid Therapy Failed to Mitigate SARS-CoV-2 Omicron Variants BA.5.2 InfectionDOI 10.21203/rs.3.rs-2717720/v1
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