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Article

Cross-species data integration to prioritize causal genes in lipid metabolism

5 Feb 2021

Abstract excerpt

PURPOSE OF REVIEW: More than one hundred loci have been identified from human genome-wide association studies (GWAS) for blood lipids. Despite the success of GWAS in identifying loci, subsequent prioritization of causal genes related to these loci remains a challenge. To address this challenge, recent work suggests that candidate causal genes within loci can be prioritized through cross-species integration using...

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PMID: 33651746
DOI: 10.1097/mol.0000000000000742

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