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Hypoxia, Autophagy and Immune Escape in the Tumor Microenvironment: From Mechanisms to Therapeutic Targeting

2026-02-18

Abstract excerpt

Tumor hypoxia is a defining hallmark of solid cancers that profoundly influences tumor progression, genomic instability, and therapeutic response. Beyond its classical roles in angiogenesis and metabolic reprogramming, hypoxia has emerged as a central determinant of the tumor immune microenvironment (TME), promoting immune exclusion and resistance to immunotherapy. Our work has uncovered tumor cell–intrinsic mecha...

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Literature Corpus work
aa9aebb5-d60b-5e2a-9809-0f4bfbf80752
DOI
10.20944/preprints202602.1320.v1
Open publication

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Hypoxia, Autophagy and Immune Escape in the Tumor Microenvironment: From Mechanisms to Therapeutic TargetingDOI 10.20944/preprints202602.1320.v1
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