Article

Impulse initiation in engrafted pluripotent stem cell-derived cardiomyocytes can stimulate the recipient heart

2023-11-15

Abstract excerpt

Transplantation of pluripotent stem cell-derived cardiomyocytes is a novel promising cell-based therapeutic approach for patients with heart failure. However, engraftment arrhythmias are a predictable life-threatening complication and represent a major hurdle for clinical translation. Catheter-based electrophysiological analysis suggested that the ventricular arrhythmias were caused by an automaticity of the trans...

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Literature Corpus work: a9af7af7-e2b7-5546-b15b-7f2ddd75d446
DOI: 10.1101/2023.11.12.566756

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