Article

Uveal Melanoma zebrafish xenograft models illustrate the mutation status-dependent effect of compound synergism or antagonism

2024-04-24

Abstract excerpt

<title>Abstract</title> <p>Purpose Uveal melanoma (UM) is the most common primary intraocular malignancy with a high probability of metastatic disease. Although excellent treatment option for primary UM are available, therapy for metastatic disease remain limited. Drug discovery studies using mouse models have thus far failed to provide therapeutic solutions, highlighting the need for novel models. Here, we opti...

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Literature Corpus work: a9ab330f-8684-59a7-a702-7bbbb6a88587
DOI: 10.21203/rs.3.rs-4292304/v1

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