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Article

Uveal Melanoma Patient-Derived Xenografts

1 Jan 2015

Abstract excerpt

The prognosis of uveal melanoma (UM) remains poor due to a high risk of metastatic disease. No effective therapies have been described for metastatic UM, and new therapies are needed to improve the outcome for these patients. To achieve this goal, new preclinical animal models are needed. Existing animal models, including genetically engineered mice and orthotopic xenograft models in immunodeficient animals, are...

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PMID: 27172261
DOI: 10.1159/000370154

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