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Identification of a Macrophage Marker Gene Signature to Evaluate Immune Infiltration and Therapeutic Response in Hepatocellular Carcinoma Based on Single-cell and Bulk RNA Sequencing Data

2023-11-08

Abstract excerpt

<h4>Background: </h4> Only a minority of hepatocellular carcinoma (HCC) patients can benefit from systemic regimens. Macrophages, which abundantly infiltrate in HCC, could mediate tumour microenvironment remodelling and immune escape, proving to be powerful weapons in combating HCC. Thus, a deeper understanding of macrophages is necessary for improving existing antitumour treatments. Methods By leveraging a serie...

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Literature Corpus work
a9876db2-3116-5f03-ad11-0da064334511
DOI
10.21203/rs.3.rs-3561035/v1
Open publication

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Identification of a Macrophage Marker Gene Signature to Evaluate Immune Infiltration and Therapeutic Response in Hepatocellular Carcinoma Based on Single-cell and Bulk RNA Sequencing DataDOI 10.21203/rs.3.rs-3561035/v1
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