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Integrated analysis of single‑cell and bulk RNA‑sequencing identifies a signature based on macrophage marker genes involved in prostate cancer prognosis and treatment responsiveness

2022-10-05

Abstract excerpt

<h4>Background: </h4> In the tumor microenvironment, tumor-associated macrophages (TAMs) interact with cancer cells and contribute to the progression of solid tumors. Nonetheless, the clinical significance of TAMs-related biomarkers in prostate cancer (PCa) is largely unexplored. The present study aimed to construct a macrophage-related signature (MRS) for predicting the prognosis of PCa patients based on macropha...

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Literature Corpus work
44c1c7f4-6adc-52a2-a7ce-399acc90ee55
DOI
10.21203/rs.3.rs-2116772/v1
Open publication

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