Back to search

Article

Tumor-Associated Macrophages (TAMs) Polarization by Single-Cell Sequencing Combined with Bulk Data in Hepatocellular Carcinoma Cell

2024-01-15

Abstract excerpt

[Objective] To investigate the expression of ALDH2 in hepatocellular carcinoma and its correlation with macrophage infiltration and with the activation of specific subtypes of macrophages. [Methods] Transcriptome and clinical data from patients with hepatocellular carcinoma were downloaded from The Cancer Genome Atlas (TCGA) and the International Cancer Genome Consortium (ICGC) databases and analyzed and collated...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
048f79de-2c0f-5be3-98c4-eada2317e495
DOI
10.20944/preprints202401.1007.v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Tumor-Associated Macrophages (TAMs) Polarization by Single-Cell Sequencing Combined with Bulk Data in Hepatocellular Carcinoma CellDOI 10.20944/preprints202401.1007.v1
Identification of a Macrophage Marker Gene Signature to Evaluate Immune Infiltration and Therapeutic Response in Hepatocellular Carcinoma Based on Single-cell and Bulk RNA Sequencing DataSemantic proximity
Single-cell transcriptome analysis reveals the key genes associated with macrophage polarization in liver cancerSemantic proximity
Identification of SPP1+ macrophages as an immune suppressor in hepatocellular carcinoma using single-cell and bulk transcriptomicsSemantic proximity
Integrated single-cell and bulk RNA sequencing analysis revealing the role of FCGR2A on prognosis and immune infiltration of hepatocellular carcinomaSemantic proximity
Gene trail of polarized M2 macrophage decodes tumor heterogeneity and recommendation for therapy of hepatocellular carcinomaSemantic proximity
M2-like tumor-associated macrophage-related biomarkers to construct a novel prognostic signature, reveal the immune landscape, and screen drugs in hepatocellular carcinomaSemantic proximity
Construction of TME and Identification of crosstalk between malignant cells and macrophages by SPP1 in hepatocellular carcinoma.Semantic proximity
Single-cell and machine learning approaches uncover intrinsic immune-evasion genes in the prognosis of hepatocellular carcinomaSemantic proximity
Eight-Gene Metabolic Signature Related with Tumor-Associated Macrophages Predicting Overall Survival for Hepatocellular CarcinomaSemantic proximity
Integrated immunogenomic analysis of single-cell and bulk tissue transcriptome profiling unravels a macrophage activation paradigm associated with immunologically and clinically distinct behaviors in ovarian cancerSemantic proximity
SLC17A2 Expression Correlates with Prognosis and Immune Infiltrates in Hepatocellular CarcinomaSemantic proximity
Unveiling the Dual Expression of Haptoglobin in Malignant Hepatocellular Carcinoma Cells through Single-Cell and Bulk RNA Sequencing AnalysisSemantic proximity
Select a neighboring publication to make it the new centre.