Article

The PI3K/AKT/mTOR signaling pathway is aberrantly activated in primary central nervous system lymphoma and correlated with a poor prognosis.

2021-11-18

Abstract excerpt

<h4>Background: </h4> Primary central nervous system lymphoma (PCNSL) is a specific subtype of non-Hodgkin lymphoma that is highly invasive and confined to the central nervous system (CNS). The vast majority of PCNSLs are diffuse large B-cell lymphomas (DLBCLs). PCNSL is a highly heterogeneous disease, and its pathogenesis has not yet been fully elucidated. Further studies are needed to guide individualized therap...

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Identifiers and source

Literature Corpus work: a9799e94-850a-55c3-8469-38bcce45a47d
DOI: 10.21203/rs.3.rs-793020/v1

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