Article

Muscle-Specific Upregulation of Timeless Mediates Exercise-Induced Amelioration of Age-Related Circadian Rhythm Disruption and Cardiac Dysfunction in Drosophila

2026-04-20

Abstract excerpt

<title>Abstract</title> The core genes of the circadian pathway, such as <italic>Timeless(Tim)</italic> , not only participate in the regulation of biological rhythms, but also play significant roles in DNA damage repair, chronic inflammation, and metabolism of cells. However, it remains unclear whether exercise can delay the age-related phenotypic degeneration by regulating muscle <italic>Tim</italic> g...

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Literature Corpus work: a94ae01c-801a-5b2a-a0e0-be83ec2d7068
DOI: 10.21203/rs.3.rs-9316587/v1

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Muscle-Specific Upregulation of Timeless Mediates Exercise-Induced Amelioration of Age-Related Circadian Rhythm Disruption and Cardiac Dysfunction in DrosophilaDOI 10.21203/rs.3.rs-9316587/v1Read

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