Article

Tumor-specific Causal Inference (TCI): A Bayesian Method for Identifying Causative Genome Alterations within Individual Tumors

2017-11-28

Abstract excerpt

Precision medicine for cancer involves identifying and targeting the somatic genome alterations (SGAs) that drive the development of an individual tumor. Much of current efforts at finding driver SGAs have involved identifying the genes that are mutated more frequently than expected among a collection of tumors. When these population-derived driver genes are altered (perhaps in particular ways) in a given tumor, t...

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Literature Corpus work: a900a3db-b763-560f-b5ac-1b84face064d
DOI: 10.1101/225631

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