Article

Single-cell transcriptomic analysis of SARS-CoV-2 reactive CD4 <sup>+</sup> T cells

2020-06-13

Abstract excerpt

<h4>ABSTRACT</h4> The contribution of CD4 + T cells to protective or pathogenic immune responses to SARS-CoV-2 infection remains unknown. Here, we present large-scale single-cell transcriptomic analysis of viral antigen-reactive CD4 + T cells from 32 COVID-19 patients. In patients with severe disease compared to mild disease, we found increased proportions of cytotoxic follicular helper (T FH ) cells and cytot...

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Literature Corpus work: a8e8b2c5-7999-5eca-9846-81ad6a696aba
DOI: 10.1101/2020.06.12.148916

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