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Investigating the role of inflammation-modulated microRNAs and signalling pathways in blood-barrier dysfunction

2012-01-01

Abstract excerpt

Cerebral endothelial cells (CEC) constitute a key cellular element of the blood- brain barrier (BBB) due to their bidirectional selective permeability that contributes to central nervous system (CNS) homeostasis. However, their specialized barrier function is altered during neuroinflammatory disorders such as multiple sclerosis (MS). Yet, the molecular mechanisms implicated in the loss of brain endothelial barrier...

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Literature Corpus work
a8c93efd-f8a2-50ab-9da2-051daf77413d
DOI
10.21954/ou.ro.0000ffe7
Open publication

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