Article

Large scale variation in the rate of <i>de novo</i> mutation, base composition, divergence and diversity in humans

2017-02-21

Abstract excerpt

It has long been suspected that the rate of mutation varies across the human genome at a large scale based on the divergence between humans and other species. It is now possible to directly investigate this question using the large number of de novo mutations (DNMs) that have been discovered in humans through the sequencing of trios. We show that there is variation in the mutation rate at the 100KB, 1MB and 10MB...

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Literature Corpus work: 1aa2ca6c-8ce6-567d-a99d-dfc564f00516
DOI: 10.1101/110452

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