Article

The Prioritization of Eleven-Nineteen-Leukemia Inhibitors as Potential Drug Candidates to Treat Acute Myeloid Leukemia

2022-12-07

Abstract excerpt

<h4>ABSTRACT</h4> Acute myeloid leukemia (AML) is the second most diagnosed and the deadliest subtype of leukemia. Recently genetic loss-of-function studies have demonstrated that a human YEATS domain-containing protein named eleven-nineteen-leukaemia (ENL) functions as a transcriptional coactivator and is essential for the proliferation of AML that harbours oncogenic multiple lineage leukemia (MLL) rearrangement...

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Literature Corpus work: a87b7e2d-9d84-5ee1-990b-dae8000ea741
DOI: 10.1101/2022.12.07.519474

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