Article

Axonal mRNA in human embryonic stem cell derived neurons

2016-07-27

Abstract excerpt

The identification of axonal mRNAs in model organisms has led to the discovery of multiple proteins synthesized within axons for functional roles such as axon guidance and injury response. The extent to which protein synthesis within the axon is conserved in humans is unknown. Here we used axon-isolating microfluidic chambers to characterize the axonal transcriptome of human embryonic stem cells (hESC-neurons) dif...

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Literature Corpus work: a852b065-a33e-575b-8398-02dba57b94a7
DOI: 10.1101/066142

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