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Article

Heritable Immunization Establishes a New Model for Pathogen Control

2024-12-22

Abstract excerpt

Heritable immunization represents a promising approach for controlling infectious diseases by embedding immunity directly into the genomes of wild species that spread human pathogens. Here, we report the genetic engineering of Mus musculus to produce a neutralizing, protective single-chain antibody against Borrelia burgdorferi , the causative agent of Lyme disease. Engineered mice stably produced a LA-2 scFv-alb...

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Identifiers and source

Literature Corpus work
a7c8324f-2cc9-57ab-a475-42f10d494be4
DOI
10.1101/2024.12.19.629026
Open publication

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Heritable Immunization Establishes a New Model for Pathogen ControlDOI 10.1101/2024.12.19.629026
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