Article

Early Prediction of Gestational Diabetes Using Integrated Cell-free DNA Features and Omics-derived Genetic Scores

2025-09-05

Abstract excerpt

<h4>Background</h4> Gestational diabetes mellitus (GDM) affects 15.6% of pregnancies globally, with Vietnam exhibiting one of the highest prevalences at 21%. Current diagnostic approaches at 24-28 weeks limit early intervention opportunities. We developed a multi-modal machine learning framework integrating cell-free DNA (cfDNA) structural features and genetic information for early GDM prediction at 10-12 weeks o...

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Literature Corpus work: a79246fd-d19e-5efc-afbb-27ebd6b5be5e
DOI: 10.1101/2025.09.03.25334985

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