Article

Development and Characterization of Ea7Mab-10: A Novel Monoclonal Antibody Targeting EphA7

2025-04-29

Abstract excerpt

Eph receptor-ephrin system is essential for embryonic, neural, and vascular development, and also plays important roles in tumor promotion or suppression. EphA7 was described as a tumor suppressor that is frequently lost in lymphomas. In contrast, EphA7 mutations have been suggested to be a driver gene in several cancers. However, the detailed molecular function has not been clarified. Therefore, monoclonal antibo...

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Literature Corpus work: a776cb52-ee3c-577e-8759-7fe9dd5277c0
DOI: 10.20944/preprints202504.2395.v1

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