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A single-cell liver atlas of Plasmodium vivax infection

19 Apr 2022

Abstract excerpt

Malaria-causing Plasmodium vivax parasites can linger in the human liver for weeks to years and reactivate to cause recurrent blood-stage infection. Although they are an important target for malaria eradication, little is known about the molecular features of replicative and non-replicative intracellular liver-stage parasites and their host cell dependence. Here, we leverage a bioengineered human microliver...

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PMID: 35443155
DOI: 10.1016/j.chom.2022.03.034

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