Article

Inhibitors of IFN Gene Stimulators (STING) Improve Intestinal Ischemia-Reperfusion Induced Acute Lung Injury by Activating AMPK Signal

2022-02-04

Abstract excerpt

<h4>Background: </h4> Acute lung injury (ALI) caused by intestinal ischemia-reperfusion is a life-threatening disease. Interferon gene stimulator ( STING ) is a cytoplasmic DNA sensor, participating in the initiation of inflammatory response. This study aims to establish whether C-176 ( STING inhibitor) improves the ALI under intestinal ischemia-reperfusion conditions. <h4>Methods: </h4>: To induce ALI, 72 C57BL/6...

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Literature Corpus work: 36c1bea8-cdd6-5293-b39e-643f8f60ce5c
DOI: 10.21203/rs.3.rs-1323161/v1

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