Article

Comparative Effectiveness Of Bedaquiline On One-Year Mortality In Rifampicin-Resistant Tuberculosis: A Target Trial Emulation

2024-08-23

Abstract excerpt

<h4>Background</h4> Three phase II clinical trials generated the evidence for recommending bedaquiline for the treatment of rifampicin-resistant tuberculosis (RR-TB). These trials were not powered to assess the effect of bedaquiline on mortality. Observational studies reported lower mortality in patients treated with bedaquiline-containing regimens but did not fully account for differences between patients who did...

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Literature Corpus work: a7056adf-df96-5349-8476-7ba59422cdd2
DOI: 10.1101/2024.08.23.24312479

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