Article

Multivariable Mendelian Randomization Analysis Reveals the Protective Effect of Restless Legs Syndrome against Lower Limb Venous Diseases and Pulmonary Embolism

2024-08-28

Abstract excerpt

Abstract Objectives: Lower limb immobility is a significant risk factor for peripheral vascular diseases, such as venous thromboembolism (VTE). Restless legs syndrome (RLS) is characterized by an irresistible urge to move the lower limbs to alleviate discomfort. The impact of RLS on lower limb vascular diseases is unclear. <h4>Methods:</h4> This study used a two-sample Mendelian Randomization (MR) approach to asse...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: a6b93ff6-3531-5e50-9fcd-7904e69717c5
DOI: 10.1101/2024.08.27.24312632

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Multivariable Mendelian Randomization Analysis Reveals the Protective Effect of Restless Legs Syndrome against Lower Limb Venous Diseases and Pulmonary EmbolismDOI 10.1101/2024.08.27.24312632Read

An insight into the causal relationship between sarcopenia-related traits and venous thromboembolism: A mendelian randomization study.Semantic proximity Read

A time sequence analysis of the relationship between cardiovascular risk factors, vascular diseases and restless legs syndrome in the general populationSemantic proximity Read

Causal effect of renal function on venous thromboembolism: a two-sample Mendelian randomization investigation.Semantic proximity Read

Genome-wide association study identifies novel restless legs syndrome susceptibility loci on 2p14 and 16q12.1.Semantic proximity Read

Restless legs syndrome: an update on genetics and future perspectives.Semantic proximity Read

Causal relationship between moderate to vigorous physical activity and venous thromboembolism.Semantic proximity Read

An update on the pathophysiology and genetics of restless legs syndromeSemantic proximity Read

Mendelian Randomization Analysis of Hemostatic Factors and Their Contribution to Peripheral Artery Disease-Brief Report.Semantic proximity Read

Taller height as a risk factor for venous thromboembolism: a Mendelian randomization meta-analysis.Semantic proximity Read

Genomic analysis identifies risk factors in restless legs syndromeSemantic proximity Read

The genetic effects of hormones modulated by the Pituitary-Thyroid/Adrenal/Gonadal axis on the risk of developing venous thromboembolism: a mendelian randomization study.Semantic proximity Read

Effect of muscle strength on deep vein thrombosis: A Mendelian randomization studySemantic proximity Read