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Article

Causal effect of renal function on venous thromboembolism: a two-sample Mendelian randomization investigation.

Journal of thrombosis and thrombolysis - 1 Jan 2022

Yuan Shuai, Bruzelius Maria, Larsson Susanna C

Abstract excerpt

Whether renal function is causally associated with venous thromboembolism (VTE) is not yet fully elucidated. We conducted a two-sample Mendelian randomization (MR) study to determine the causal effect of renal function, measured as estimated glomerular filtration rate (eGFR), on VTE. Single-nucleotide polymorphisms associated with eGFR were selected as instrumental variables at the genome-wide significance level...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34043151
DOI: 10.1007/s11239-021-02494-4
PMCID: PMC8791872

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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