Article

CXCR4 enhances the inhibitory effects of bone mesenchymal stem cells on lung cell apoptosis in a rat model of smoking-induced COPD

2022-08-11

Abstract excerpt

<h4>Objective: </h4> Chronic obstructive pulmonary disease (COPD) is the 3rd leading cause of death worldwide, and treatments are unsatisfactory, resulting in a major economic burden. Cellular therapy is commonly used for lung disease. We investigated treatment with CXCR4-overexpressing BMSCs during COPD model establishment. Methods We extracted and purified BMSCs from SD rats. Apoptosis induced by COPD was estab...

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Literature Corpus work: a6b18d50-f729-5a4d-95f6-26dc80d5f6b3
DOI: 10.21203/rs.3.rs-1910750/v1

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