Article
Mesenchymal stem cell therapy for the treatment of chronic obstructive pulmonary disease.
Expert opinion on biological therapy - 1 May 2010
D'Agostino Bruno, Sullo Nikol, Siniscalco Dario, De Angelis Antonella, Rossi Francesco
Abstract excerpt
Recent studies have revealed that adult stem cells such as bone marrow-derived cells contribute to lung tissue regeneration and protection, and thus administration of exogenous stem/progenitor cells may be a potent next-generation therapy for COPD. Pathogenesis of COPD is characterized by an upregulation of inflammatory processes leading to irreversible events such as apoptosis of epithelial cells, proteolysis of...
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