Article

Norbornene homopolymerization limits cell spreading in thiol-ene photoclick hydrogels

2025-04-24

Abstract excerpt

<h4>ABSTRACT</h4> Thiol-ene click chemistry is a powerful tool for designing hydrogels mimicking the mechanical and biochemical properties of 3D cellular microenvironments. The high selectivity of thiol-norbornene step-growth polymerization enables precise control of crosslinking mechanism, circumventing the alkene homopolymerization present in other systems that can prevent encapsulated cell spreading. Limited s...

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Literature Corpus work: a68638f9-3e7f-5cfa-b4a0-8c71a16e144d
DOI: 10.1101/2025.04.18.648735

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