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Article

Hydrophobic nanoparticles improve permeability of cell-encapsulating poly(ethylene glycol) hydrogels while maintaining patternability.

Proceedings of the National Academy of Sciences of the United States of America - 30 Nov 2010

Lee Wonjae, Cho Nam-Joon, Xiong Anming, Glenn Jeffrey S, Frank Curtis W

Abstract excerpt

Cell encapsulating poly(ethylene glycol) hydrogels represent a promising approach for constructing 3D cultures designed to more closely approximate in vivo tissue environment. Improved strategies are needed, however, to optimally balance hydrogel permeability to support metabolic activities of encapsulated cells, while maintaining patternability to restore key aspects of tissue architecture. Herein, we have...

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Identifiers

PMID: 21071674
DOI: 10.1073/pnas.1005211107
PMCID: PMC2996449

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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