Article

Patterned ELR-Gelatin Hydrogels Enable Rapid Endothelial Monolayer Formation via Bioactive Matrix Chemistry and Surface Topography

2026-03-24

Abstract excerpt

<h4>ABSTRACT</h4> The endothelialization of organ-on-chip platforms and vascular implants is often limited by slow cell attachment and unstable monolayer formation. This work presents a scalable workflow that imprints micro- and nano-gratings into elastin-like recombinamer (ELR)-based hydrogels, enabling rapid endothelial cell capture and accelerating monolayer formation within 14 days. Three gelatin-ELR formulat...

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Literature Corpus work: 3bd9bad8-36bb-5ed4-ba1f-8801fe0be511
DOI: 10.64898/2026.03.22.713452

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