Article

Multi-omic analysis identifies a multi-step pathology in a case of multiple chorangioma syndrome in monochorionic twins

2024-12-05

Abstract excerpt

<h4>Background</h4> Chorangiomas, benign proliferative capillary lesions in the placenta, occur in approximately 1% of births, typically as a solitary nodule. In rare cases, multiple nodules develop, posing risks of fetal heart failure, hydrops fetalis, and intrauterine death due to altered placental hemodynamics. Although genetic and hypoxic factors have been hypothesized to drive aberrant angiogenesis, definitiv...

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Literature Corpus work: a67988cc-38fe-53e5-adfb-545e0c4bf10c
DOI: 10.1101/2024.12.03.24318397

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