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Article

Whole-brain comparison of rodent and human brains using spatial transcriptomics

2022-03-18

Abstract excerpt

The ever-increasing use of mouse models in preclinical neuroscience research calls for an improvement in the methods used to translate findings between mouse and human brains. Using openly accessible brain-wide transcriptomic data sets, we evaluated the similarity of mouse and human brain regions on the basis of homologous gene expression. Our results suggest that mouse-human homologous genes capture broad pattern...

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Identifiers and source

Literature Corpus work
a6626ac4-5d4b-5b67-8960-aab96d98323a
DOI
10.1101/2022.03.18.484766
Open publication

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Whole-brain comparison of rodent and human brains using spatial transcriptomicsDOI 10.1101/2022.03.18.484766
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