Article
TransBrain: A computational framework for translating brain-wide phenotypes between humans and mice
2025-01-27
Abstract excerpt
Despite remarkable advances in whole-brain imaging technologies, the lack of quantitative approaches to bridge rodent preclinical and human studies remains a critical challenge. Here we present TransBrain, a computational framework enabling bidirectional translation of brain-wide phenotypes between humans and mice. TransBrain improves human-mice homology mapping accuracy through: (1) a novel detached region-specif...
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Identifiers and source
- Literature Corpus work
- 23b7817e-bc90-55ab-992b-9b87141e541f
- DOI
- 10.1101/2025.01.27.635016