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Article

Conservation of regional gene expression in mouse and human brain.

PLoS genetics - 20 Apr 2007

Strand Andrew D, Aragaki Aaron K, Baquet Zachary C, Hodges Angela, Cunningham Philip, Holmans Peter, Jones Kevin R, Jones Lesley, Kooperberg Charles, Olson James M

Abstract excerpt

Many neurodegenerative diseases have a hallmark regional and cellular pathology. Gene expression analysis of healthy tissues may provide clues to the differences that distinguish resistant and sensitive tissues and cell types. Comparative analysis of gene expression in healthy mouse and human brain provides a framework to explore the ability of mice to model diseases of the human brain. It may also aid in...

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Identifiers

PMID: 17447843
DOI: 10.1371/journal.pgen.0030059
PMCID: PMC1853119

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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