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Article

Space‐time considerations for hematopoietic stem cell transplantation

24 Jul 2008

Abstract excerpt

The mammalian blood system contains a multitude of distinct mature cell lineages adapted to serving diverse functional roles. Mutations that abrogate the development or function of one or more of these lineages can lead to profound adverse consequences, such as immunodeficiency, autoimmunity, or anemia. Replacement of hematopoietic stem cells (HSC) that carry such mutations with HSC from a healthy donor can...

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PMID: 18651698
DOI: 10.1002/eji.200838383

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