Article

CRISPR and Compound Screens in a Novel Ex Vivo Tissue Model Identify DDR1 and ETA as Regulators of Cancer Cell Invasion

2026-01-20

Abstract excerpt

<title>Abstract</title> Background. Bladder cancer (BC) can be characterized clinically as either non-muscle-invasive (NMIBC) or muscle-invasive (MIBC). While NMIBC generally has a favorable prognosis, MIBC is characterized by high morbidity and mortality. Understanding the molecular determinants of tumor invasion is critical, yet research is hampered by the limitations of current experimental models. Stand...

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Literature Corpus work: a5f598b0-162b-5575-8c7d-77a1cf42d34c
DOI: 10.21203/rs.3.rs-8250186/v1

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