Article

LncRNA-ADAM11 regulates the vascular endothelial cell senescence and promotes the development of intracranial aneurysm via MiR-223-3p/NLRP3 pathway

2022-04-01

Abstract excerpt

Intracranial aneurysms (IAs) are the localized dilatations of intracranial arteries because of the weaknesses of the endothelial layer. It causes subarachnoid hemorrhage (SAH), which accounted for 80% of total SAH and has 50% fatality rate. Cell senescence, especially endothelial cells senescence, is closely related to the occurrence of vascular diseases. However, the relationship of endothelial cell senescence an...

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Literature Corpus work: a5c39db4-eb15-581a-874b-ebfa7a11db06
DOI: 10.21203/rs.3.rs-1494919/v1

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