Article
Integrative analysis of senescence-related genes in endothelial cells of Cerebral Ischemic Stroke patients
2024-07-18
Abstract excerpt
<title>Abstract</title> <p>Growing evidence points that aging is a predominant risk factor for Cerebral Ischemic Stroke (CIS), caused by endothelial cells dysfunction and senescence. Our research was aimed to explore potential vital cellar senescence-related differentially expressed genes (CSRDEGs) as diagnostic biomarkers for CIS by bioinformatic analysis. We acquired 8058 DRGs from the combined dataset(GSE22255...
Topics
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- Atherosclerosis and Cardiovascular Diseases
- Autophagy in Disease and Therapy
- Cancer-related molecular mechanisms research
- Endoplasmic Reticulum Stress and Disease
- Ferroptosis and cancer prognosis
- Kruppel-like factors research
- Neuroinflammation and Neurodegeneration Mechanisms
- Telomeres, Telomerase, and Senescence
Identifiers and source
- Literature Corpus work
- 19ccdd2f-e342-5ceb-8050-09cabb183caa
- DOI
- 10.21203/rs.3.rs-4577549/v1
