Article

The first prospective registry-based cohort study focused on type 2 diabetes mellitus patients from high-altitude regions: The HLA-DR study protocol

2023-09-15

Abstract excerpt

<h4>Background: </h4> : Diabetes is the leading cause of disease burden in many countries, owing to its microvascular and macrovascular complications. Tibetans who have lived on Qinghai-Tibet Plateau for thousands of years have genetically adapted to their hypoxic high-altitude environment through positive natural selection for a hyporesponsive hypoxia-inducible factor (HIF) pathway. Highlanders have lower prevale...

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Literature Corpus work: a5b22ac3-65cf-5da1-83c3-8ad11322bb45
DOI: 10.21203/rs.3.rs-3278775/v1

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