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Article

HIF2A Variants Were Associated with Different Levels of High-Altitude Hypoxia among Native Tibetans.

PloS one - 1 Jan 2015

Basang Zhuoma, Wang Boyang, Li Lei, Yang La, Liu Lan, Cui Chaoying, Lanzi Gongga, Yuzhen Nima, Duo Ji, Zheng Hongxiang, Wang Yi, Xu Shuhua, Jin Li, Wang Xiaofeng

Abstract excerpt

Hypoxia inducible factors, including HIF1A and HIF2A, play central roles in response to high-altitude hypoxia and genetic variants of HIF1A or HIF2A were associated with high-altitude sickness or adaptation. However, it remains to determine whether they are associated with tolerance to different levels of high-altitude selection pressure among native Tibetans. We recruited 189 Tibetan subjects living at 2,700...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26368009
DOI: 10.1371/journal.pone.0137956
PMCID: PMC4569405

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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